Thermo Fisher Scientific ARFGAP1 Monoclonal Antibody (OTI1H4), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ArfGAP1 is a 406-amino-acid regulatory protein containing an Arf-GAP domain involved in activation of the GTPase activity of ADP ribosylation factor (ARF).
It promotes hydrolysis of ARF1-bound GTP and is essential for dissociation of coat proteins from Golgi-derived membranes and vesicles, playing a key role in membrane trafficking and vesicle transport.
Its activity is stimulated by phosphoinositides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported, and ArfGAP1 is ubiquitously expressed in most tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.