Thermo Fisher Scientific MRG Polyclonal Antibody
Human MRGBP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, PBS buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 46–75 amino acids from the central region of human MRGBP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900911 |
Target Information
C20orf20 (also known as MRG/MORF4L-binding protein or Up-regulated in colon cancer 4, Urcc4) is a 204 amino acid nuclear protein belonging to the EAF7 family.
It is a component of the NuA4 histone acetyltransferase (HAT) complex, involved in transcriptional activation of specific genes through acetylation of nucleosomal histones H4 and H2A.
This modification can alter nucleosome–DNA interactions and facilitate recruitment of transcription-regulating proteins.
The NuA4 complex is implicated in transcriptional programs associated with oncogene and proto-oncogene-mediated growth induction, tumor suppressor-mediated growth arrest, replicative senescence, apoptosis, and DNA repair.
C20orf20 undergoes phosphorylation and acetylation, with an apparent molecular weight of approximately 25–30 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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