Thermo Fisher Scientific SIRP gamma Polyclonal Antibody
인간 SIRP gamma 단백질을 인식하는 Sheep 유래 Polyclonal 항체. Western blot 및 Flow cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며 PBS와 5% 트레할로오스 완충액 포함. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant human SIRP gamma/CD172g Val64–Ser364, (Val263Ala) and (Ser286Leu) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576834 |
Product Specific Information
- In direct ELISAs, less than 5% cross-reactivity with recombinant human SIRP alpha, SIRP beta 1, and recombinant mouse SIRP alpha is observed.
- Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein belonging to the immunoglobulin gene superfamily. It is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail similar to SIRP beta, but unlike SIRP beta, it does not require DAP12 for expression at the cell surface. Like SIRP alpha, CD172g binds to CD47 inducing apoptosis and is involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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