Thermo Fisher Scientific IL23A Recombinant Rabbit Monoclonal Antibody (1F6)
IL23A 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 재조합 형식으로 높은 특이성과 재현성을 제공합니다. 인간 시료 반응성이 있으며, 액상 형태로 -20°C 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1F6 |
| Immunogen | A synthesized peptide derived from human IL23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.55 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092862 |
Target Information
IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19. The p19 subunit, like p35 of IL-12, is biologically inactive by itself. IL-23 interacts with IL-12Rβ1 and an additional β2-like receptor subunit with a STAT4 binding domain, termed IL-23R. It is secreted by activated mouse and human dendritic cells.
Biological activities of mouse IL-23 differ from IL-12: mouse IL-23 does not induce significant IFN-γ but promotes proliferation of memory T cells and production of IL-17. In humans, IL-23 induces proliferation of memory T cells and moderate IFN-γ production compared to IL-12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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