Thermo Fisher Scientific DIRAS3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DIRAS3. Recombinant protein control fragment (Product #RP-94375). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DIRAS3,uniProtId:O95661-1,ncbiNodeId:9606,antigenRange:74-145,antigenLength:229,antigenImageFileName:PA5-56122_DIRAS3_O95661-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56122_DIRAS3_O95661-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640612

Product Specific Information

Immunogen sequence: YCQLLGCSHG VLSLHITDSK SGDGNRALQR HVIARGHAFV LVYSVTKKET LEELKAFYEL ICKIKGNNLH KF

Highest antigen sequence identity to the following orthologs: Mouse - 44%, Rat - 44%.

Target Information

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.