Thermo Fisher Scientific CD2 Monoclonal Antibody (OTI9D1), TrueMAB
Human CD2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot과 Flow cytometry에 사용 가능. 동결건조 형태로 제공되며, PBS와 trehalose buffer에 보관. 연구용으로 T 세포 표지 및 CD2 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9D1 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human CD2 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD2 (LFA-2) is a monomeric surface antigen (MW 45–58 kDa) of human T-lymphocytes, expressed on over 95% of thymocytes and some NK cells, but not on B lymphocytes.
It mediates adhesion between T cells and antigen-presenting cells via interaction with CD58.
CD2 expression increases upon T cell activation, enhancing adhesion and immune response.
CD2 deficiency is linked to reduced intestinal inflammation and certain immune disorders, including thymus-related immunodeficiency and penile squamous cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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