Thermo Fisher Scientific TMEM100 Monoclonal Antibody (OTI2D3), TrueMAB
TMEM100 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot과 IHC(파라핀 절편)에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인간 시료 반응성이 있으며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D3 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human TMEM100 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TMEM100 plays a role in embryonic arterial endothelium differentiation and vascular morphogenesis via the ACVRL1 receptor-dependent signaling pathway, stimulated by bone morphogenetic proteins such as GDF2/BMP9 and BMP10.
It is involved in nociception regulation by modulating the interaction between TRPA1 and TRPV1 in dorsal root ganglia neurons, enhancing TRPA1 activity by reducing its inhibition by TRPV1.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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