Thermo Fisher Scientific STK39 Monoclonal Antibody (OTI2E10), TrueMAB
인간 STK39 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 세포 스트레스 반응 연구 및 p38 MAPK 경로 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E10 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human STK39 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
STK39 (STLK3) participates in the cellular stress response pathway. It is activated by hypotonic stress, leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway, and its interaction with p38 decreases under stress conditions. It functions as an intermediate in stress response and has been identified as an independent risk factor for hypertension in men. Intragenic SNPs of STK39 may contribute to blood pressure regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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