Thermo Fisher Scientific MHC Class I Recombinant Rabbit Monoclonal Antibody (ARC1291)
Thermo Fisher Scientific의 ARC1291은 인간 MHC Class I(HLA-A/B)을 인식하는 재조합 토끼 단클론 항체입니다. Western blot, ICC/IF, ELISA에 적합하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1291 |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human MHC Class I (HLA-A/B) (UniProt ID: P04439) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849612 |
Product Specific Information
Immunogen sequence:
KETLQRTDPP KTHMTHHPIS DHEATLRCWA LGFYPAEITL TWQRDGEDQT QDTELVETRP AGDGTFQKWA AVVVPSGEEQ RYTCHVQHEG LPKPLTLRWE L
Target Information
Avian MHC Class I molecules (B-F antigens) consist of a polymorphic alpha-chain bound to beta2-microglobulin. These molecules are expressed on most nucleated cells and present endogenously synthesized antigenic peptides to CD8+ cytotoxic T cells.
This antibody also reacts with turkey MHC Class I.
HLA and MHC antibodies are crucial in Immunopeptidomics for identifying and characterizing neoantigens via LC-MS/MS analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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