Thermo Fisher Scientific CDKN2C Recombinant Rabbit Monoclonal Antibody (ARC1289)
CDKN2C 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, HEK293 세포에서 발현된 IgG 형식의 항체입니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1289 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–120 of human CDKN2C/p18-INK4C (UniProt ID: P42773) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849611 |
Product Specific Information
Immunogen sequence:
MAEPWGNELA SAAARGDLEQ LTSLLQNNVN VNAQNGFGRT ALQVMKLGNP EIARRLLLRG ANPDLKDRTG FAVIHDAARA GFLDTLQTLL EFQADVNIED NEGNLPLHLA AKEGHLRVVE
Target Information
The protein encoded by CDKN2C is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent kinase activation, thereby functioning as a regulator of cell cycle G1 progression. Overexpression suppresses human cell growth in correlation with wild-type RB1 function. Knockout mouse studies indicate roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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