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Thermo Fisher Scientific EPB41L2 Polyclonal Antibody
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Thermo Fisher Scientific EPB41L2 Polyclonal Antibody

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인간 EPB41L2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 액상 형태로 1 mg/mL 농도이며 PBS/glycerol 버퍼에 저장. 세포골격 단백질 연구에 적합한 연구용 항체.

카탈로그번호
PA5106614
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오전 06:32
Thermo Fisher Scientific PA5106614 EPB41L2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원

Thermo Fisher Scientific · Thermo Fisher Scientific EPB41L2 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC-P) 1:50–1:200
Immunocytochemistry (ICC/IF) 1:100–1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthesized peptide derived from human EPB41L2 (Accession O43491), corresponding to amino acid residues E573–Y623
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS, pH 7.4, with 50% glycerol
Contains 0.02% sodium azide
Storage Conditions –20°C
Shipping Conditions Wet ice
RRID AB_2854282

Product Specific Information

This antibody detects endogenous levels of total EPB41L2.

Target Information

The 4.1 gene family encodes multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N, and 4.1B), predominantly expressed in the nervous system.

  • 4.1G stabilizes spectrin–actin interactions and is associated with hereditary elliptocytosis.
  • 4.1R is essential for maintaining erythrocyte shape and membrane mechanical properties.
  • Both 4.1R and 4.1G are distributed in unique patterns in the cerebellum and modulate neuronal membrane mechanical properties by promoting fodrin/actin association.
  • 4.1N (EPB41L1) and 4.1B (EPB41L3) are strongly expressed in the brain.
    Antibodies to 4.1N detect multiple forms enriched in postsynaptic density preparations, while antibodies to 4.1B detect two forms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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