Thermo Fisher Scientific ABCA6 Polyclonal Antibody
Human ABCA6 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 사용 가능. 고순도 Affinity chromatography로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ABCA6 (Accession Q8N139), corresponding to amino acid residues V1213–A1263 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854279 |
Product Specific Information
Antibody detects endogenous levels of total ABCA6.
Target Information
The ATP-binding cassette (ABC) superfamily consists of transmembrane proteins involved in energy-dependent transport of various substrates across membranes.
ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. It is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis.
ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. It is present at highest levels in adult liver, with significant expression in many adult tissues and fetal lung, kidney, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-106611_ABCA6_Q8N139-1_Rabbit_PDP.jpeg)
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