Thermo Fisher Scientific PRDX2 Polyclonal Antibody
인간, 마우스, 랫트 반응성의 PRDX2 폴리클로날 항체로 Western Blot, IHC, ICC/IF에 사용 가능. 합성 펩타이드 면역원 기반, 액상 형태, 1 mg/mL 농도. 친화 크로마토그래피로 정제되었으며 -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRDX2 (Accession P32119), corresponding to amino acid residues D166–N198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854565 |
Product Specific Information
Antibody detects endogenous levels of total Peroxiredoxin 2.
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins are categorized into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx subgroups. Except for Prx VI (1-Cys), other 2-Cys Prx isotypes exhibit thioredoxin-dependent peroxidase activity using thioredoxin, thioredoxin reductase, and NADPH as reducing agents. Mammalian Prxs are 20–30 kDa and vary in subcellular localization: Prx I, II, and VI in cytosol; Prx III in mitochondria; Prx IV in ER and secretion; Prx V distributed in peroxisome, mitochondria, and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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