Thermo Fisher Scientific CDC45L Polyclonal Antibody
CDC45L 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 시 500 µg/mL 농도를 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human CDC45L recombinant protein (Position: E166–A431) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746137 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by this gene shows strong similarity to Saccharomyces cerevisiae Cdc45, an essential protein required for the initiation of DNA replication. Cdc45 is part of a conserved multiprotein complex including Cdc6/Cdc18, MCM proteins, and DNA polymerase, which are crucial for early DNA replication steps in eukaryotes. This protein interacts with MCM7 and DNA polymerase alpha, and studies in Xenopus suggest its role in loading DNA polymerase alpha onto chromatin. Multiple polyadenylation sites have been reported for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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