Thermo Fisher Scientific OTX2 Polyclonal Antibody
Western blot, IHC(P), IHC(F)에 적합한 OTX2 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 뇌 및 감각기관 발달 관련 연구에 적합. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse OTX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792910 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%)
- Positive Control: Y79
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
OTX2 is a 289 amino acid protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors.
It has two known alternative splice variants with distinct isoforms, though presence of other isoforms cannot be excluded.
The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and sensory organs.
It may bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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