Thermo Fisher Scientific TFG Monoclonal Antibody (OTI2C3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

TFG protein is a human homolog of mouse TFG protein. It features an N-terminal coiled-coil domain, a SPYGQ-rich region, and octicosapeptide repeats.
Research indicates TFG modulates SHP-1 activity and is a novel component of the NF-κB pathway. Though its physiological roles remain unclear, TFG is known to interact with proteins such as TANK and NEMO.
TFG was first identified as a partner of NTRK1 and participates in forming the thyroid TRK-T3 oncogene and oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.