Thermo Fisher Scientific MHC II Monoclonal Antibody (MK-D6)
마우스 MHC Class II (I-Ad) 인식 단일클론 항체로, ICC/IF, 유세포분석, 기능적 분석에 적합합니다. 단백질 A/G로 정제된 액상 항체이며, 4°C에서 보관합니다. 인간 시료와 반응하지 않으며 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MHC II Monoclonal Antibody (MK-D6)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | |
| Flow Cytometry (Flow) | 0.5–1 µg/10⁶ cells | |
| Functional Assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MK-D6 |
| Immunogen | Spleen cells from B10.D2 mice immunized with MHC Class II (I-Ad) antigens |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Human
Target Information
MHC class II molecules are heterodimers composed of non-covalently associated alpha (31–34 kDa) and beta (26–29 kDa) chains.
Antigen presentation by MHC class II involves two processes:
- Endocytosed antigens are degraded into peptides by lysosomal proteases.
- Class II molecules, initially bound to invariant chain (Ii), acquire peptide-binding capacity after Ii degradation in peptide-containing compartments.
MHC class II molecules present exogenous antigens to CD4⁺ T lymphocytes (typically T helper cells).
CD4 interacts with non-polymorphic residues of MHC class II.
HLA and MHC antibodies are essential in Immunopeptidomics, enabling identification and characterization of neoantigens using high-performance liquid chromatography coupled with tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 관련 이미지가 있을 경우 이 섹션에 배치합니다.)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.