Thermo Fisher Scientific Major Basic Protein (PRG2) Monoclonal Antibody (OTI1C12)
인간 PRG2 단백질(아미노산 17-222)을 인식하는 Mouse IgG2a 단일클론 항체입니다. Western blot에 1:500 희석으로 사용 가능하며, 액상 형태로 제공됩니다. PBS, 글리세롤, BSA 함유 저장용액에 보관하며, -20°C에서 안정적으로 저장됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 17–222 of human PRG2 (NP_002719) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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