
Thermo Fisher Scientific SORT1 Monoclonal Antibody (OTI3H4), TrueMAB
Human SORT1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. TrueMAB 포맷으로 고특이성 및 재현성 제공. Affinity chromatography로 정제된 액상 항체이며, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 34–300 of human SORT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. It is required for protein transport from the Golgi apparatus to the lysosomes and endosomes, independent of the mannose-6-phosphate receptor (M6PR). Sortilin promotes neuronal apoptosis by mediating endocytosis of proBDNF and proNGFB and also acts as a receptor for neurotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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