Thermo Fisher Scientific MSL2 Monoclonal Antibody (OTI3B11), TrueMAB
MSL2 단백질을 타깃으로 하는 Mouse IgG2a 단클론 항체. Western blot에 최적화되어 있으며 Human, Mouse, Rat 시료에 반응. Lyophilized 형태로 제공되며 PBS buffer에 trehalose 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B11 |
| Immunogen | Full length human recombinant protein of human MSL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MSL2 is a component of the histone acetyltransferase complex responsible for histone H4 acetylation at lysine 16, influencing chromatin structure. It acts as an E3 ubiquitin ligase promoting monoubiquitination of histone H2B at Lys-35 (H2BK34Ub), stimulating H3 methylation at Lys-4 and Lys-79, leading to gene activation such as HOXA9 and MEIS1.
[UniProt: Q9HCI7-1]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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