Thermo Fisher Scientific GABBR2 Polyclonal Antibody
Thermo Fisher Scientific의 GABBR2 Polyclonal Antibody는 인간 시료에 반응하며, Rabbit IgG 기반의 액상 항체입니다. Western blot에 적합하고, GABA-B 수용체 연구에 활용됩니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Suggested Positive Control: Human brain protein
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to the 105 kDa GABAbR2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2278891 |
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release, ion channel activity, and adenylyl cyclase function.
This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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