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Thermo Fisher Scientific NF1 Polyclonal Antibody
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NF1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. N-terminal peptide (aa 1–50)를 면역원으로 사용. 연구용으로만 사용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 02:27
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Thermo Fisher Scientific PA146246 NF1 Polyclonal Antibody 500 ul pk판매 단위 pk ·
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628,600원VAT 포함 691,460원
Thermo Fisher Scientific · Thermo Fisher Scientific NF1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An N-terminal peptide of Neurofibromin 1 (within amino acids 1–50). [Uniprot: P21359] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2149657 |
Product Specific Information
- Western blot: Bands at 220–240 kDa and an uncharacterized higher MW band at 450 kDa observed.
- IHC (Frozen): Antigen retrieval not required.
- IHC (Paraffin): Antigen retrieval with trypsin or citrate improves staining.
Target Information
The encoded protein is a type I integral membrane protein localized between the endoplasmic reticulum and Golgi apparatus, likely recycling between these compartments. It acts as a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are linked to combined factor V–factor VIII deficiency, a rare autosomal recessive disorder with reduced levels of both coagulation factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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