Thermo Fisher Scientific TFEB Polyclonal Antibody
TFEB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, IP 등에 사용 가능. 인간 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | 2.5 µg/mL | View 2 publications |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid synthetic peptide near the amino terminus of human TFEB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551712 |
Product Specific Information
- Suggested positive control: A549 cell lysate
- PA5-34360 can be used with blocking peptide PEP-1403.
Target Information
Transcription factor EB (TFEB) is a member of the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors.
Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1.
Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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