Thermo Fisher Scientific BCL11A Polyclonal Antibody, MaxPab
BCL11A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간 시료 반응성. Affinity chromatography로 정제된 액상 형태로, PBS buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BCL11A (NP_612569.1, 1–243 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ CQMNFPLGDI LIFIEHKRKQ CNGSLCLEKA VDKPPSPSPI EMKKASNPVE VGIQVTPEDD DCLSTSSRGI CPKQEHIADK LLHWRGLSSP RSAHGALIPT PGMSAEYAPQ GICKDEPSSY TCTTCKQPFT SAWFLLQHAQ NTHGLRIYLE SEHGSPLTPR VLHTPPFGVV PRELKMCGSF RMEAREPLSS EKI
Target Information
This gene encodes a C2H2 type zinc-finger protein similar to mouse Bcl11a/Evi9. The mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis. Translocations associated with B-cell malignancies also deregulate its expression. Multiple transcript variants encoding several isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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