Thermo Fisher Scientific CALML5 Monoclonal Antibody (2F10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2F10

Immunogen

CALML5 (AAH39172, 1 a.a. approximately 146 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CALML5,uniProtId:Q9NZT1-1,ncbiNodeId:9606,antigenRange:1-146,antigenLength:146,antigenImageFileName:H00051806-M16_CALML5_Q9NZT1-1_House_mouse.svg,antigenImageFileNamePDP:H00051806-M16_CALML5_Q9NZT1-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAGELTPEEE AQYKKAFSAV DTDGNGTINA QELGAALKAT GKNLSEAQLR KLISEVDGDG DGEISFQEFL TAARKARAGL EDLQVAFRAF DQDGDGHITV DELRRAMAGL GQPLPQEELD AMIREADVDQ DGRVNYEEFA RMLAQE

Target Information

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.