Thermo Fisher Scientific SSEA1 Monoclonal Antibody (MC-480), DyLight 550
DyLight 550 형광 표지를 가진 SSEA1 (CD15) 단클론 항체로 인간 및 마우스 시료에 반응합니다. Flow Cytometry에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 안정적 PBS buffer와 sodium azide 보존제로 구성되어 4°C에서 보관 가능합니다.
- 카탈로그번호
- MA1022D550
- 판매단위
- pk
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Thermo Fisher Scientific SSEA1 Monoclonal Antibody (MC-480), DyLight 550
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:50–1:500
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MC-480 |
| Immunogen | BALB/c mouse immunized with F9 teratocarcinoma stem cells (X-irradiated) |
| Conjugate | DyLight™ 550 |
| Excitation/Emission Max | 556 / 570 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography - MBP |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.02% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536695 |
Additional Formats
Product Specific Information
MA1-022-D550 has been successfully used in flow cytometry on mouse and human samples.
Target Information
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisaccharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of various cell types, e.g., granulocytes, mast cells, monocytes, macrophages, gastric mucosa cells, nervous system, and various tumor cells.
Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation based on calcium-dependent Le(x)-Le(x) interaction, which is involved in embryo compaction or autoaggregation of teratocarcinoma cells.
Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins.
CD15 expression has been extensively used to confirm diagnosis of Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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