Thermo Fisher Scientific SSEA4 Monoclonal Antibody (MC-813-70), PE
인간 SSEA-4 항원을 인식하는 단클론 항체로, PE 형광 표지되어 유세포분석에 적합합니다. 배아줄기세포 및 iPS 세포 표지 연구에 활용되며, 높은 특이성과 재현성을 제공합니다. 단백질 A 정제, PBS/BSA 완충액에 보관됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:50–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MC-813-70 |
| Immunogen | Human embryonal carcinoma cell line 2102Ep |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536691 |
Additional Formats
- Unconjugated
- Alexa Fluor 647
- DyLight 488
- DyLight 550
- DyLight 650
- Custom conjugation available on request
Product Specific Information
MA1-021-PE has been successfully used in ICC/IF and flow cytometry applications on human samples.
Target Information
SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen expressed along with SSEA-3, TRA-1-60, and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells, and induced pluripotent stem cells (iPS).
In human cells, these markers are down-regulated during differentiation, while SSEA-1 is absent in undifferentiated stem cells and upregulated after retinoic acid-mediated differentiation.
Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation, while SSEA-3 and SSEA-4 expression increase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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