Thermo Fisher Scientific TRIB1 Polyclonal Antibody
TRIB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography로 정제되었습니다. 인간 시료에 반응하며, 안정적인 액상 형태로 -20°C에서 보관 가능합니다.
- 카탈로그번호
- PA587662
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIB1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:4,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 203–372 of human TRIB1 (NP_0794711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804331 |
Product Specific Information
- Immunogen sequence:
LGDLKLRKFV FSTEERTQLR LESLEDTHIM KGEDDALSDK HGCPAYVSPE ILNTTGTYSG KAADVWSLGV MLYTLLVGRY PFHDSDPSAL FSKIRRGQFC IPEHISPKAR CLIRSLLRRE PSERLTAPEI LLHPWFESVL EPGYIDSEIG TSDQIVPEYQ EDSDISSFFC - Positive Samples: U-87MG, BxPC-3, Raji
Target Information
TRIB1 (also called gprotein coupled receptor induced, skip1, gig2, c8fwATP) functions in protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities.
Overexpression of TRIB1 in HeLa cells repressed basal IL8 promoter activity by inhibiting AP1 activity. TRIB1 inhibited oncogenic Ras-driven AP1 activation and MEKK1-mediated AP1 activation while enhancing ERK activation.
Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced TRIB1 stability via TRIB-MAPKK interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.