Thermo Fisher Scientific TMPRSS11D Polyclonal Antibody
TMPRSS11D 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 세포막 단백질 검출에 유용합니다. 고순도 Affinity Chromatography 정제 및 안정한 PBS/glycerol buffer로 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 42–292 of human TMPRSS11D (NP_004253.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.24 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804329 |
Product Specific Information
Immunogen sequence:
AFDQKSYFYR SSFQLLNVEY NSQLNSPATQ EYRTLSGRIE SLITKTFKES NLRNQFIRAH VAKLRQDGSG VRADVVMKFQ FTRNNNGASM KSRIESVLRQ MLNNSGNLEI NPSTEITSLT DQAAANWLIN ECGAGPDLIT LSEQRILGGT EAEEGSWPWQ VSLRLNNAHH CGGSLINNMW ILTAAHCFRS NSNPRDWIAT SGISTTFPKL RMRVRNILIH NNYKSATHEN DIALVRLENS VTFTKDIHSV C
Positive Samples:
HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney
Cellular Location:
Cell membrane, Single-pass type II membrane protein
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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