Thermo Fisher Scientific TMPRSS11D Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_0042531) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMPRSS11D,uniProtId:O60235-1,ncbiNodeId:9606,antigenRange:42-292,antigenLength:418,antigenImageFileName:PA5-87660_TMPRSS11D_O60235-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87660_TMPRSS11D_O60235-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.24 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804329

Product Specific Information

Immunogen sequence: AFDQKSYFYR SSFQLLNVEY NSQLNSPATQ EYRTLSGRIE SLITKTFKES NLRNQFIRAH VAKLRQDGSG VRADVVMKFQ FTRNNNGASM KSRIESVLRQ MLNNSGNLEI NPSTEITSLT DQAAANWLIN ECGAGPDLIT LSEQRILGGT EAEEGSWPWQ VSLRLNNAHH CGGSLINNMW ILTAAHCFRS NSNPRDWIAT SGISTTFPKL RMRVRNILIH NNYKSATHEN DIALVRLENS VTFTKDIHSV C; Positive Samples: HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney; Cellular Location: Cell membrane, Single-pass type II membrane protein

Target Information

The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.