Thermo Fisher Scientific SLC4A8/SLC4A10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SLC4A8(Accession Q2Y0W8), corresponding to amino acid residues F1040-S1090. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC4A8/SLC4A10,uniProtId:Q2Y0W8-1,ncbiNodeId:9606,antigenRange:1040-1090,antigenLength:1093,antigenImageFileName:PA5-101904_SLC4A8SLC4A10_Q2Y0W8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101904_SLC4A8SLC4A10_Q2Y0W8-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:SLC4A8/SLC4A10,uniProtId:Q6U841-1,ncbiNodeId:9606,antigenRange:1118,antigenLength:1118,antigenImageFileName:PA5-101904_SLC4A8SLC4A10_Q6U841-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101904_SLC4A8SLC4A10_Q6U841-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2851336

Product Specific Information

Antibody detects endogenous levels of total SLC4A8/10.

Target Information

This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.