Thermo Fisher Scientific SLC4A8/SLC4A10 Polyclonal Antibody
SLC4A8/SLC4A10 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에 반응합니다. WB 및 ICC/IF에 사용 가능하며, 친화 크로마토그래피로 정제된 액상 항체입니다. PBS/glycerol buffer에 보존되며 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC4A8 (Accession Q2Y0W8), corresponding to amino acid residues F1040–S1090 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851336 |
Product Specific Information
Antibody detects endogenous levels of total SLC4A8/10.
Target Information
This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE), though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [Provided by RefSeq, May 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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