Thermo Fisher Scientific ATP1A2 Polyclonal Antibody
ATP1A2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 PBS/glycerol 버퍼로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATP1A2 (Accession P50993), corresponding to amino acid residues R3–Y53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851334 |
Product Specific Information
Antibody detects endogenous levels of total ATP1A2.
Target Information
Atp1a2 encodes an Na⁺/K⁺ ATPase, a membrane protein composed of alpha and beta subunits. This enzyme maintains essential electrochemical gradients within cells by actively transporting sodium (Na⁺) and potassium (K⁺) ions.
The Atp1a2 gene product belongs to the P-type cation transport ATPase family, specifically the Na⁺/K⁺-ATPases subfamily. These ion pumps are critical for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability in nerve and muscle cells.
The catalytic alpha subunit is encoded by multiple genes, and Atp1a2 encodes the alpha 2 subunit. Mutations in Atp1a2 are associated with familial hemiplegic migraine type 2 and alternating hemiplegia of childhood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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