Thermo Fisher Scientific MPP5 Polyclonal Antibody
MPP5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 사용 가능. Human, Mouse, Rat에 반응하며 세포 극성 유지 연구에 적합. 항원 친화 크로마토그래피로 정제, PBS/glycerol 버퍼에 저장. 연구용으로만 사용.
- 카탈로그번호
- PA530966
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–203 of Human MPP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548440 |
Product Specific Information
- Recommended positive controls: NT2D1, U87-MG, SK-N-SH
- Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (85%), Chicken (85%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis.
This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons.
It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells.
Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes.
In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells.
MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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