Thermo Fisher Scientific SIRT2 Monoclonal Antibody (5H11H9)
SIRT2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry, ELISA에 사용 가능. Human 시료에 반응하며 Protein G로 정제된 액상 형태. 1 mg/mL 농도, PBS buffer에 0.05% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H11H9 |
| Immunogen | Purified recombinant fragment of human SIRT2 (AA: 275–389) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090733 |
Target Information
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) involved in gene silencing, cell cycle regulation, and DNA damage repair.
SIRT2 may function as a tumor suppressor in human gliomas and serve as a molecular marker for these cells.
It also acts as a redox sensor regulating muscle gene expression in response to food intake and exercise, and participates in the phosphorylation cascade during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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