Thermo Fisher Scientific XRCC3 Monoclonal Antibody (OTI5B11), TrueMAB
인간 XRCC3 단백질(aa 1-235)에 특이적인 Mouse IgG1 단일클론 항체. Western blot 검증 완료. 동결건조 형태로 제공되며 PBS, trehalose buffer에 보존. DNA 손상 복구 연구 및 단백질 안정성 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–235 of human XRCC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The XRCC3 gene encodes a RecA/Rad51-related protein involved in homologous recombination to maintain chromosome stability and repair DNA damage. It complements repair-deficient mutants sensitive to DNA-damaging agents and is associated with cancer susceptibility in certain radiosensitive individuals. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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