Thermo Fisher Scientific MAP3K9 Polyclonal Antibody
MAP3K9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제된 고순도 항체로, -20°C에서 안정적으로 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MAP3K9, amino acids 451–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway. It plays an important role in cellular response cascades to environmental changes. Once activated, MAP3K9 acts as an upstream activator of the MKK/JNK signal transduction cascade through phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7, which subsequently activate JNKs. The MKK/JNK signaling pathway regulates stress responses via activator protein-1 (JUN) and GATA4 transcription factors. MAP3K9 also participates in mitochondrial death signaling pathways, including cytochrome c release leading to apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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