Thermo Fisher Scientific SNAP alpha Recombinant Rabbit Monoclonal Antibody (ARC2382)
SNAP alpha 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 안정적인 PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2382 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 201–295 of human Alpha SNAP (P54920) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897785 |
Product Specific Information
- Positive Samples: HepG2, A-549, Mouse brain, Rat brain
- Immunogen sequence:
SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE CKLMKKLLEA HEEQNVDSYT ESVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR
Target Information
SNAPs (soluble NSF attachment proteins) act with SNAREs (SNAP receptors) and NSF (N-ethylmaleimide-sensitive fusion protein) to mediate vesicle fusion with target membranes in processes such as synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion, and transcytotic vesicle-to-plasma membrane transport.
During vesicle docking, vesicle SNARE binds to target SNARE, then α-SNAP (or β-SNAP in brain) binds to this complex, recruiting NSF to form a 20S fusion particle. ATP hydrolysis by NSF initiates membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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