Thermo Fisher Scientific KLC1 Polyclonal Antibody
Thermo Fisher Scientific의 KLC1 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며, WB, IHC, ICC/IF 등 다양한 응용에 사용됩니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 장기 보관 시 -20°C에서 안정성을 유지합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human KLC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720480 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, transporting various cargos along microtubules toward their plus ends. Heavy chains provide motor activity, while light chains bind to cargos.
This gene encodes a member of the kinesin light chain family that associates with kinesin heavy chain through an N-terminal domain. Six tetratricopeptide repeat (TPR) motifs are involved in cargo binding, including vesicles, mitochondria, and the Golgi complex.
Kinesin light chains act as adapter molecules rather than motors. Although previously named “kinesin 2,” this gene is not part of the kinesin-2 heavy chain subfamily. Extensive alternative splicing produces isoforms with different C-termini, proposed to bind various cargos; however, the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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