
Thermo Fisher Scientific IGFBP3 Polyclonal Antibody
IGFBP3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(F)에서 검증됨. Human, Mouse, Rat에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액에 1% BSA, 20% 글리세롤 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 84–291 of Human IGFBP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544666 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji, mouse plasma
- Predicted reactivity: Mouse (89%), Rat (88%), Pig (83%), Rhesus Monkey (99%), Bovine (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
IGFBP3는 insulin-like growth factor binding protein (IGFBP) 패밀리에 속하는 유전자로, IGFBP 도메인과 thyroglobulin type-I 도메인을 모두 포함하는 단백질을 암호화합니다.
이 단백질은 insulin-like growth factor acid-labile subunit (IGFALS) 및 IGF-I 또는 II와 삼중 복합체를 형성하여 혈장 내에서 순환하며 IGF의 반감기를 연장하고 세포 표면 수용체와의 상호작용을 조절합니다.
다양한 전사적 스플라이싱 변이체가 보고되었으며, IGFBP3 관련 질환으로는 Insulin-Like Growth Factor I 및 Acid-Labile Subunit Deficiency가 있습니다.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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