Thermo Fisher Scientific BAK Recombinant Rabbit Monoclonal Antibody (7Q3T8)
Human Bak 단백질(aa 11-82)에 특이적인 재조합 Rabbit Monoclonal 항체. Western blot 및 ELISA에 적합하며, 높은 특이성과 재현성을 제공. 액상 형태로 0.75 mg/mL 농도, -20°C에서 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7Q3T8 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 11–82 of human Bak (NP_0011791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2897752 |
Product Specific Information
- Positive Samples: HeLa, AGS
- Immunogen sequence:
RQECGEPALP SASEEQVAQD TEEVFRSYVF YRHQQEQEAE GVAAPADPEM VTLPLQPSST MGQVGRQLAI IG
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and the release of cytochrome c. It also interacts with the tumor suppressor P53 after exposure to cell stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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