Thermo Fisher Scientific DDX3 Monoclonal Antibody
Western blot에 적합한 DDX3 단클론 항체로, 인간 DDX3X 재조합 단백질을 면역원으로 제작되었습니다. 다양한 세포주에서 양성 반응을 보이며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human DDX3X |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Positive Samples:
Jurkat, K-562, HeLa, NIH/3T3, Mouse kidney, Mouse lung, Mouse heart
Target Information
The protein encoded by this gene belongs to the large DEAD-box protein family, defined by the conserved Asp-Glu-Ala-Asp (DEAD) motif, and exhibits ATP-dependent RNA helicase activity. It shows RNA-independent ATPase activity, and unlike most DEAD-box helicases, its ATPase activity is stimulated by both RNA and DNA. This protein functions in both the nucleus and cytoplasm, participating in transcriptional regulation, mRNP assembly, pre-mRNA splicing, mRNA export, translation, cellular signaling, and viral replication. Dysregulation of this gene has been implicated in tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes related to both this gene and DDX3Y are found on chromosome 4 and the X chromosome. Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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