Thermo Fisher Scientific CARD11 Recombinant Rabbit Monoclonal Antibody (ARC1680)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1680

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1055-1154 of human CARD11 (Q9BXL7) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CARD11,uniProtId:Q9BXL7-1,ncbiNodeId:9606,antigenRange:1055-1154,antigenLength:1154,antigenImageFileName:MA5-35829_CARD11_Q9BXL7-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35829_CARD11_Q9BXL7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849729

Product Specific Information

Immunogen sequence: EAGIGCTRDL IKSNIYPIVL FIRVCEKNIK RFRKLLPRPE TEEEFLRVCR LKEKELEALP CLYATVEPDM WGSVEELLRV VKDKIGEEQR KTIWVDEDQL

Target Information

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.