Thermo Fisher Scientific ANO5 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human ANO5 protein. Validated for IHC (paraffin) with high specificity. Supplied as liquid, 0.3 mg/mL in PBS with glycerol. Suitable for research use in studying ANO5-related diseases.
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- PA563619
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- pk
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Applications
Tested Applications and Dilutions
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANO5. Recombinant protein control fragment (Product # RP-97462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638027 |
Product Specific Information
Immunogen sequence:
NTSSTEICDP EIGGQMIMCP LCDQVCDYWR LNSTCLASKF SHLFDNE
Antigen sequence identity:
- Mouse: 87%
- Rat: 85%
Target Information
Ano5 does not exhibit calcium-activated chloride channel (CaCC) activity. The Ano5 gene encodes a member of the anoctamin family of transmembrane proteins. The Ano5 protein is likely a calcium-activated chloride channel. Mutations in the Ano5 gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described for Ano5.
Diseases associated with ANO5:
- Gnathodiaphyseal Dysplasia
- Miyoshi Muscular Dystrophy 3
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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