Thermo Fisher Scientific VGAT Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human VGAT. Recombinant protein control fragment (Product #RP-99348). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VGAT,uniProtId:Q9H598-1,ncbiNodeId:9606,antigenRange:13-103,antigenLength:525,antigenImageFileName:PA5-63620_VGAT_Q9H598-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63620_VGAT_Q9H598-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649424

Product Specific Information

Immunogen sequence: ATSVSNKSQA KMSGMFARMG FQAATDEEAV GFAHCDDLDF EHRQGLQMDI LKAEGEPCGD EGAEAPVEGD IHYQRGSGAP LPPSGSKDQV G

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.

Target Information

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.