
Thermo Fisher Scientific Paxillin Polyclonal Antibody
다중종(인간, 마우스, 랫트)에 반응하는 Rabbit Polyclonal Paxillin 항체로, WB, IHC, ICC/IF에 적합합니다. 고순도(>95%) 항원 친화 크로마토그래피 정제 제품이며, 액상 형태로 1 mg/mL 농도 제공합니다. 세포 부착 및 신호 전달 연구용으로 적합합니다.
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Thermo Fisher Scientific Paxillin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids at the N-terminus of Human Paxillin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803367 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. Its tyrosine phosphorylation is influenced by changes in cell-cell adhesion. Paxillin associates with FAK and Crk through its SH2 domain, independently of the extracellular matrix. Initially discovered in fibroblasts, paxillin phosphorylation may also play a role in neurite extension during differentiation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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