Thermo Fisher Scientific PDE4A Monoclonal Antibody (OTI8B7), TrueMAB
Human PDE4A 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Lyophilized 형태이며 1 mg/mL 농도, PBS buffer 포함. 연구용으로 신호전달 관련 PDE4A 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B7 |
| Immunogen | Full length human recombinant protein of human PDE4A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cyclic nucleotides act as second messengers mediating cellular responses to extracellular signals such as hormones, light, and neurotransmitters.
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide levels and play key roles in signal transduction.
PDE4A is a class IV cAMP-specific phosphodiesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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