Thermo Fisher Scientific SUPT4H1 Monoclonal Antibody (OTI5F12), TrueMAB
SUPT4H1 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot에 최적화되어 있습니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, PBS buffer(8% trehalose)로 안정화되어 있습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F12 |
| Immunogen | Full length human recombinant protein of human SUPT4H1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.
DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.
It cooperates with the negative elongation factor complex (NELF) to enhance transcriptional pausing near promoters, facilitating assembly of elongation-competent RNA polymerase II complexes.
DSIF and NELF inhibit transcription elongation factor TFIIS/S-II, promoting transcriptional pausing.
DSIF also supports elongation activation by HIV-1 Tat and prevents premature transcript release from the HIV-1 LTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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