Thermo Fisher Scientific P170/p-Glycoprotein Polyclonal Antibody
인간 p-Glycoprotein(ABCB1)을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 안정화 버퍼에 0.5 mg/mL 농도로 제공됩니다. 세포 내 위치는 Cytoplasm이며, 인간 소뇌를 양성 대조로 사용할 수 있습니다.
- 카탈로그번호
- 500-13734
- 판매단위
- pk
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Thermo Fisher Scientific P170/p-Glycoprotein Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.1–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from internal segment (1150–1258aa) of human p170 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human cerebellum
- Cellular Location: Cytoplasm
Target Information
The membrane-associated protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein, part of the MDR/TAP subfamily, functions as an ATP-dependent drug efflux pump with broad substrate specificity, contributing to multidrug resistance and reduced drug accumulation in resistant cells. It also serves as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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