Thermo Fisher Scientific VIM Monoclonal Antibody (1H6)
휴먼 Vimentin 단백질을 인식하는 마우스 단클론 항체. Western blot 및 ELISA에 적합하며, PBS(pH 7.4) 용액 형태로 제공. 친화 크로마토그래피로 정제되었으며, 보존제 무첨가. -20°C 보관, 동결/해동 반복 피할 것.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | A synthetic peptide corresponding to human VIM (Vimentin, UniProt ID: P08670-1, antigen range: 366–390, antigen length: 466) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence: QDEIQNMKEE MARHLREYQD LLNVK
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular transport of proteins between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin induces filament breakdown and cytoskeletal rearrangements, facilitating cholesterol transport to mitochondria and enhancing steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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