Thermo Fisher Scientific IL13 Monoclonal Antibody (OTI6D3), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. It regulates inflammatory and immune responses by down-regulating macrophage activity and inhibiting pro-inflammatory cytokine and chemokine production.
IL-13 is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. It also influences B cell maturation, differentiation, CD23 and MHC class II expression, and promotes IgE isotype switching. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The genes encoding these cytokines form a cluster on chromosome 5q, with IL-13 located near IL4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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