Thermo Fisher Scientific CYB5R3 Monoclonal Antibody (OTI2A10), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CYB5R3 (NADH-cytochrome b5 reductase 3, diaphorase 1) is a 301-amino-acid protein encoded by the human CYB5R3 gene.
It belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occurring isoforms:

• Isoform 1: Anchored to the cytoplasmic side of the endoplasmic reticulum and mitochondrial outer membrane
• Isoform 2: Soluble form found in erythrocytes

CYB5R3 is involved in fatty acid desaturation and elongation, cholesterol biosynthesis, drug metabolism, and methemoglobin reduction in erythrocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.